{"product_id":"elk-es9094-cbx8-rabbit-pab","title":"CBX8 rabbit pAb","description":"\u003cp\u003eCBX8 rabbit pAb is an ELK Biotechnology antibody for research workflows involving CBX8.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003efunction:Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.,similarity:Contains 1 chromo domain.,subunit:Component of chromatin-associated class II polycomb repressive complex 1 (PRC1\/hPRC-H) at least composed of PCGF2\/RNF110, BMI1\/PCGF4, CBX2\/M33, CBX4\/PC2, CBX8\/PC3, PHC1, PHC2, PHC3, SCMH1, RING1 and RNF2\/RING2. Interacts with MLLT3.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCBX8 Polyclonal Antibody detects endogenous levels of protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187497120084,"sku":"ABM109941","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187497152852,"sku":"ABM100077","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES9094-c-1.jpg?v=1782055772","url":"https:\/\/www.abmium.com\/products\/elk-es9094-cbx8-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}