{"product_id":"elk-es8629-hnf-4alpha-gamma-acetyl-lys127-79-rabbit-pab","title":"HNF-4α\/γ (Acetyl Lys127\/79) rabbit pAb","description":"\u003cp\u003eHNF-4α\/γ (Acetyl Lys127\/79) rabbit pAb is an ELK Biotechnology antibody for research workflows involving HNF-4α\/γ.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eThis antibody detects endogenous levels of HNF-4α\/γ at Human:K127\/79;Mouse:K127\/79;Rat:K127, It doesn't reacte with total protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of mouse-lung mouse-brain mouse-heart Hela mouse-liver lysate, antibody was diluted at 500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187440595284,"sku":"ABM109753","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187440628052,"sku":"ABM99889","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES8629-c-1.jpg?v=1782055161","url":"https:\/\/www.abmium.com\/products\/elk-es8629-hnf-4alpha-gamma-acetyl-lys127-79-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}