{"product_id":"elk-es7965-cyclin-e2-rabbit-pab","title":"Cyclin E2 rabbit pAb","description":"\u003cp\u003eCyclin E2 rabbit pAb is an ELK Biotechnology antibody for research workflows involving Cyclin E2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP\/KIP family of CDK inhibitors, and plays a role in cell cycle G1\/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCyclin E2 Polyclonal Antibody detects endogenous levels of Cyclin E2 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunofluorescence analysis of NIH\/3T3 cells, using Cyclin E2 Antibody. The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue, using Cyclin E2 Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from COLO and Jurkat cells, using Cyclin E2 Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187398193492,"sku":"ABM109536","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187398226260,"sku":"ABM99672","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7965-c-1.jpg?v=1782054653","url":"https:\/\/www.abmium.com\/products\/elk-es7965-cyclin-e2-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}