{"product_id":"elk-es7822-mnk1-phospho-thr255-rabbit-pab","title":"Mnk1 (phospho Thr255) rabbit pAb","description":"\u003cp\u003eMnk1 (phospho Thr255) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Mnk1.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMAP kinase interacting serine\/threonine kinase 1(MKNK1) Homo sapiens This gene encodes a Ser\/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Mnk1 (T255) Polyclonal Antibody detects endogenous levels of Mnk1 protein only when phosphorylated at T255.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eEnzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using MNK1 (Phospho-Thr255) Antibody | Western blot analysis of lysates from HeLa cells treated with Adriamycin 0.5ug\/ml 24h, using MNK1 (Phospho-Thr255) Antibody. The lane on the right is blocked with the phospho peptide. | Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187305132372,"sku":"ABM109479","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187305165140,"sku":"ABM99615","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7822-c-1.jpg?v=1782052092","url":"https:\/\/www.abmium.com\/products\/elk-es7822-mnk1-phospho-thr255-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}