{"product_id":"elk-es7643-camkiialpha-delta-rabbit-pab","title":"CaMKIIα\/δ rabbit pAb","description":"\u003cp\u003eCaMKIIα\/δ rabbit pAb is an ELK Biotechnology antibody for research workflows involving CaMK2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe product of this gene belongs to the serine\/threonine protein kinases family, and to the Ca(2+)\/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCaMKIIα\/δ Polyclonal Antibody detects endogenous levels of CaMKIIα\/δ protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of NIH-3T3\/K562 cells using CaMKIIα\/δ Polyclonal Antibody diluted at 1:500 | Immunofluorescence analysis of MCF7 cells, using CaMK2 alpha\/delta Antibody. The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CaMK2 alpha\/delta Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from NIH\/3T3 and K562 cells, using CaMK2 alpha\/delta Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187299365204,"sku":"ABM109417","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187299397972,"sku":"ABM99553","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7643-c-1.jpg?v=1782051929","url":"https:\/\/www.abmium.com\/products\/elk-es7643-camkiialpha-delta-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}