{"product_id":"elk-es7583-chsy2-rabbit-pab","title":"CHSY2 rabbit pAb","description":"\u003cp\u003eCHSY2 rabbit pAb is an ELK Biotechnology antibody for research workflows involving CHSY2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ecatalytic activity:UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl-(1-\u0026gt;4)-beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl-(1-\u0026gt;3)-N-acetyl-beta-D-galactosaminyl-(1-\u0026gt;4)-beta-D-glucuronosyl-proteoglycan.,catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl-(1-\u0026gt;3)-N-acetyl-beta-D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl-(1-\u0026gt;4)-beta-D-glucuronosyl-(1-\u0026gt;3)-N-acetyl-beta-D-galactosaminyl-proteoglycan.,cofactor:Divalent cations. Highest activities are measured with manganese. Can also utilize cobalt.,function:Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer.,online information:GlycoGene database,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family.,subunit:Binds CHSY1.,tissue specificity:Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCHSY2 Polyclonal Antibody detects endogenous levels of CHSY2 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunofluorescence analysis of MCF7 cells, using CHSY2 Antibody. The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using CHSY2 Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from LOVO and K562 cells, using CHSY2 Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187294122324,"sku":"ABM109388","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187294155092,"sku":"ABM99524","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7583-c-1.jpg?v=1782052206","url":"https:\/\/www.abmium.com\/products\/elk-es7583-chsy2-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}