{"product_id":"elk-es7557-tubulin-alpha1-3-4-phospho-tyr272-rabbit-pab","title":"Tubulin α1\/3\/4 (phospho Tyr272) rabbit pAb","description":"\u003cp\u003eTubulin α1\/3\/4 (phospho Tyr272) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Tubulin α.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMicrotubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Tubulin α1\/3\/4 (Y272) Polyclonal Antibody detects endogenous levels of Tubulin α1\/3\/4 protein only when phosphorylated at Y272.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from Rat brain, using TUBA1\/3\/4 (Phospho-Tyr272) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187293270356,"sku":"ABM109378","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187293303124,"sku":"ABM99514","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7557-c-1.jpg?v=1782052202","url":"https:\/\/www.abmium.com\/products\/elk-es7557-tubulin-alpha1-3-4-phospho-tyr272-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}