{"product_id":"elk-es7526-14-3-3-beta-phospho-ser184-186-rabbit-pab","title":"14-3-3 β\/ζ (phospho Ser184\/186) rabbit pAb","description":"\u003cp\u003e14-3-3 β\/ζ (phospho Ser184\/186) rabbit pAb is an ELK Biotechnology antibody for research workflows involving 14-3-3 β\/ζ.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-14-3-3 β\/ζ (S184\/186) Polyclonal Antibody detects endogenous levels of 14-3-3 β\/ζ protein only when phosphorylated at S184\/186.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from RAW264.7 cells treated with UV 15', using 14-3-3 beta\/zeta (Phospho-Ser184\/186) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187292614996,"sku":"ABM109369","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187292647764,"sku":"ABM99505","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7526-c-1.jpg?v=1782051835","url":"https:\/\/www.abmium.com\/products\/elk-es7526-14-3-3-beta-phospho-ser184-186-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}