{"product_id":"elk-es7501-ezrin-phospho-tyr353-rabbit-pab","title":"Ezrin (phospho Tyr353) rabbit pAb","description":"\u003cp\u003eEzrin (phospho Tyr353) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Ezrin.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Ezrin (Y353) Polyclonal Antibody detects endogenous levels of Ezrin protein only when phosphorylated at Y353.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from A431 cells treated with EGF 200ng\/ml 30', using Ezrin (Phospho-Tyr353) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187287273812,"sku":"ABM109354","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187287306580,"sku":"ABM99490","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7501-c-1.jpg?v=1782051797","url":"https:\/\/www.abmium.com\/products\/elk-es7501-ezrin-phospho-tyr353-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}