{"product_id":"elk-es7309-lkb1-phospho-thr189-rabbit-pab","title":"LKB1 (phospho Thr189) rabbit pAb","description":"\u003cp\u003eLKB1 (phospho Thr189) rabbit pAb is an ELK Biotechnology antibody for research workflows involving LKB1.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene, which encodes a member of the serine\/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-LKB1 (T189) Polyclonal Antibody detects endogenous levels of LKB1 protein only when phosphorylated at T189.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of 3T3 cells using Phospho-LKB1 (T189) Polyclonal Antibody | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using LKB1 (Phospho-Thr189) Antibody | Western blot analysis of lysates from NIH\/3T3 cells treated with PMA 125ng\/ml 30', using LKB1 (Phospho-Thr189) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187282784596,"sku":"ABM109297","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187282817364,"sku":"ABM99433","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7309-c-1.jpg?v=1782051689","url":"https:\/\/www.abmium.com\/products\/elk-es7309-lkb1-phospho-thr189-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}