{"product_id":"elk-es7306-krs-1-2-phospho-thr183-rabbit-pab","title":"Krs-1\/2 (phospho Thr183) rabbit pAb","description":"\u003cp\u003eKrs-1\/2 (phospho Thr183) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Krs-1\/2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eserine\/threonine kinase 3(STK3) Homo sapiens This gene encodes a serine\/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Krs-1\/2 (T183) Polyclonal Antibody detects endogenous levels of Krs-1\/2 protein only when phosphorylated at T183.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of 293 cells using Phospho-Krs-1\/2 (T183) Polyclonal Antibody | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Mst1\/2 (Phospho-Thr183) Antibody | Immunohistochemistry analysis of paraffin-embedded human brain, using Mst1\/2 (Phospho-Thr183) Antibody. The picture on the right is blocked with the phospho peptide. | Western blot analysis of lysates from 293 cells treated with H2O2 100uM 15', using Mst1\/2 (Phospho-Thr183) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187282719060,"sku":"ABM109296","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187282751828,"sku":"ABM99432","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7306-c-1.jpg?v=1782051687","url":"https:\/\/www.abmium.com\/products\/elk-es7306-krs-1-2-phospho-thr183-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}