{"product_id":"elk-es7240-bmx-phospho-tyr566-rabbit-pab","title":"Bmx (phospho Tyr566) rabbit pAb","description":"\u003cp\u003eBmx (phospho Tyr566) rabbit pAb is an ELK Biotechnology antibody for research workflows involving ETK.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Bmx (Y566) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y566.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of 4T1 using p-Bmx (Y566) antibody. | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using ETK (Phospho-Tyr566) Antibody | Immunohistochemistry analysis of paraffin-embedded human thyroid gland, using ETK (Phospho-Tyr566) Antibody. The picture on the right is blocked with the phospho peptide. | Western blot analysis of lysates from HeLa cells treated with Serum 20% 15', using ETK (Phospho-Tyr566) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187279671636,"sku":"ABM109277","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187279704404,"sku":"ABM99413","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7240-c-1.jpg?v=1782051617","url":"https:\/\/www.abmium.com\/products\/elk-es7240-bmx-phospho-tyr566-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}