{"product_id":"elk-es7089-p70-s6-kinase-alpha-phospho-thr444-rabbit-pab","title":"p70 S6 kinase α (phospho Thr444) rabbit pAb","description":"\u003cp\u003ep70 S6 kinase α (phospho Thr444) rabbit pAb is an ELK Biotechnology antibody for research workflows involving p70 S6 kinase α.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine\/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-p70 S6 kinase α (T444) Polyclonal Antibody detects endogenous levels of p70 S6 kinase α protein only when phosphorylated at T444.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of LOVO using p-p70 S6 kinase α (T444) antibody. Antibody was diluted at 1:500 | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using p70 S6 Kinase (Phospho-Thr421) Antibody | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using p70 S6 Kinase (Phospho-Thr421) Antibody. The picture on the right is blocked with the phospho peptide. | Western blot analysis of lysates from NIH\/3T3 cells treated with EGF 200ng\/ml 30', using p70 S6 Kinase (Phospho-Thr421) Antibody. The lane on the left is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187271709012,"sku":"ABM109213","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187271741780,"sku":"ABM99349","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES7089-c-1.jpg?v=1782051484","url":"https:\/\/www.abmium.com\/products\/elk-es7089-p70-s6-kinase-alpha-phospho-thr444-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}