{"product_id":"elk-es6897-pth-pthrp-r-rabbit-pab","title":"PTH\/PTHrP-R rabbit pAb","description":"\u003cp\u003ePTH\/PTHrP-R rabbit pAb is an ELK Biotechnology antibody for research workflows involving PTH\/PTHrP-R.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePTH\/PTHrP-R Polyclonal Antibody detects endogenous levels of PTH\/PTHrP-R protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of COLO cells using PTH\/PTHrP-R Polyclonal Antibody diluted at 1:1000 | Immunofluorescence analysis of MCF7 cells, using PTHR1 Antibody. The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PTHR1 Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from Jurkat cells, using PTHR1 Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"HRP \/ 100µL","offer_id":56187253588308,"sku":"ABM109142","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"HRP \/ 50µL","offer_id":56187253621076,"sku":"ABM99278","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES6897-c-1.jpg?v=1782051303","url":"https:\/\/www.abmium.com\/products\/elk-es6897-pth-pthrp-r-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}