{"product_id":"elk-es6354-septin-2-rabbit-pab","title":"Septin 2 rabbit pAb","description":"\u003cp\u003eSeptin 2 rabbit pAb is an ELK Biotechnology antibody for research workflows involving Septin 2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003efunction:Required for normal progress through mitosis. Involved in cytokinesis.,similarity:Belongs to the septin family.,subcellular location:Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localised to fibrous or granular structures, depending on the growth state of the cell.,subunit:Monomer, and homodimer. Nucleotide binding promotes dimerization. Heterohexamer composed of two heterotrimers containing one copy each of SEPT2, SEPT6 and SEPT7. The asymmetrical heterotrimers associate head-to-head to form a hexameric unit that assembles into filaments.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eSeptin 2 Polyclonal Antibody detects endogenous levels of Septin 2 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from Jurkat and MCF-7 cells, using SEPT2 Antibody. The lane on the right is blocked with the synthesized peptide. | Western blot analysis of the lysates from HepG2 cells using SEPT2 antibody. | Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187229438292,"sku":"ABM108950","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187229471060,"sku":"ABM99086","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES6354-c-1.jpg?v=1782050856","url":"https:\/\/www.abmium.com\/products\/elk-es6354-septin-2-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}