{"product_id":"elk-es6302-b-myb-phospho-ser577-rabbit-pab","title":"B-Myb (phospho Ser577) rabbit pAb","description":"\u003cp\u003eB-Myb (phospho Ser577) rabbit pAb is an ELK Biotechnology antibody for research workflows involving B-Myb.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A\/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-B-Myb (S577) Polyclonal Antibody detects endogenous levels of B-Myb protein only when phosphorylated at S577.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eEnzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using B-Myb (Phospho-Ser577\/581) Antibody | Immunofluorescence analysis of HeLa cells, using B-Myb (Phospho-Ser577\/581) Antibody. The picture on the right is blocked with the phospho peptide. | Western blot analysis of lysates from K562 cells, using B-Myb (Phospho-Ser577\/581) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187228225876,"sku":"ABM108937","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187228258644,"sku":"ABM99073","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES6302-c-1.jpg?v=1782050840","url":"https:\/\/www.abmium.com\/products\/elk-es6302-b-myb-phospho-ser577-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}