{"product_id":"elk-es5958-cleaved-iti-h1-d672-rabbit-pab","title":"Cleaved-ITI-H1 (D672) rabbit pAb","description":"\u003cp\u003eCleaved-ITI-H1 (D672) rabbit pAb is an ELK Biotechnology antibody for research workflows involving ITI-H1.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the inter-alpha-trypsin inhibitor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the heavy chain of the inter-alpha-trypsin inhibitor complex, which is secreted by hepatocytes into the blood. The heavy chain also interacts with hyaluronan, and this interaction may play a role in ovulation and fertilization, and has been implicated in multiple inflammatory diseases. This gene is present in a gene cluster on chromosome 3. [provided by RefSeq, Nov 2015],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCleaved-ITI-H1 (D672) Polyclonal Antibody detects endogenous levels of fragment of activated ITI-H1 protein resulting from cleavage adjacent to D672.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using ITIH1 (Cleaved-Asp672) Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187208794452,"sku":"ABM108798","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187208827220,"sku":"ABM98934","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES5958-c-1.jpg?v=1782050437","url":"https:\/\/www.abmium.com\/products\/elk-es5958-cleaved-iti-h1-d672-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}