{"product_id":"elk-es5578-cadherin-20-rabbit-pab","title":"Cadherin-20 rabbit pAb","description":"\u003cp\u003eCadherin-20 rabbit pAb is an ELK Biotechnology antibody for research workflows involving Cadherin-20.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCadherin-20 Polyclonal Antibody detects endogenous levels of Cadherin-20 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of CDH20 Antibody. The lane on the right is blocked with the CDH20 peptide. | Immunohistochemistryt analysis of paraffin-embedded human brain, using CDH20 Antibody. The lane on the right is blocked with the CDH20 peptide. | Immunofluorescence analysis of NIH\/3T3 cells, using CDH20 Antibody. The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDH20 Antibody. The picture on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187176845652,"sku":"ABM108635","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187176878420,"sku":"ABM98771","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES5578-c-1.jpg?v=1782050093","url":"https:\/\/www.abmium.com\/products\/elk-es5578-cadherin-20-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}