{"product_id":"elk-es5422-gab-1-phospho-tyr659-rabbit-pab","title":"Gab 1 (phospho Tyr659) rabbit pAb","description":"\u003cp\u003eGab 1 (phospho Tyr659) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Gab 1.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eGRB2 associated binding protein 1(GAB1) Homo sapiens The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Gab 1 (Y659) Polyclonal Antibody detects endogenous levels of Gab 1 protein only when phosphorylated at Y659.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of 3T3 cells using Phospho-Gab 1 (Y659) Polyclonal Antibody | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using GAB1 (Phospho-Tyr659) Antibody | Immunofluorescence analysis of HepG2 cell, using GAB1 (Phospho-Tyr659) Antibody. The lane on the right is blocked with the GAB1 (Phospho-Tyr659) peptide. | Immunohistochemistry analysis of paraffin-embedded human breast cancer, using GAB1 (Phospho-Tyr659) Antibody. The picture on the right is blocked with the GAB1 (Phospho-Tyr659) peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56187086668116,"sku":"ABM108566","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56187086700884,"sku":"ABM98702","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES5422-c-1.jpg?v=1782049918","url":"https:\/\/www.abmium.com\/products\/elk-es5422-gab-1-phospho-tyr659-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}