{"product_id":"elk-es4631-machr-m2-rabbit-pab","title":"mAChR M2 rabbit pAb","description":"\u003cp\u003emAChR M2 rabbit pAb is an ELK Biotechnology antibody for research workflows involving mAChR M2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003emAChR M2 Polyclonal Antibody detects endogenous levels of mAChR M2 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of HeLa cells using mAChR M2 Polyclonal Antibody | Immunofluorescence analysis of LOVO cells, using CHRM2 Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from HeLa and MCF-7 cells, using CHRM2 Antibody. The lane on the right is blocked with the synthesized peptide. | Western blot analysis of the lysates from HUVECcells using CHRM2 antibody.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186711671124,"sku":"ABM108232","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186711703892,"sku":"ABM98368","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES4631-c-1.jpg?v=1782047542","url":"https:\/\/www.abmium.com\/products\/elk-es4631-machr-m2-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}