{"product_id":"elk-es4076-btk-rabbit-pab","title":"Btk rabbit pAb","description":"\u003cp\u003eBtk rabbit pAb is an ELK Biotechnology antibody for research workflows involving Btk.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eBtk Polyclonal Antibody detects endogenous levels of Btk protein only when non-phosphorylation at Y550.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186634600788,"sku":"ABM107861","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186634633556,"sku":"ABM97997","price":131.54,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/elk-es4076-btk-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}