{"product_id":"elk-es4007-cxcr-3-rabbit-pab","title":"CXCR-3 rabbit pAb","description":"\u003cp\u003eCXCR-3 rabbit pAb is an ELK Biotechnology antibody for research workflows involving CXCR-3.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eC-X-C motif chemokine receptor 3(CXCR3) Homo sapiens This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9\/Mig (monokine induced by interferon-g), CXCL10\/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11\/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4\/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCXCR-3 Polyclonal Antibody detects endogenous levels of CXCR-3 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunohistochemical analysis of paraffin-embedded chiken tissue, the picture was kindly provided by our customer. | Western Blot analysis of K562 cells using CXCR-3 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 | Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100 | Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186629325140,"sku":"ABM107812","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186629357908,"sku":"ABM97948","price":131.54,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/elk-es4007-cxcr-3-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}