{"product_id":"elk-es3961-snap-23-rabbit-pab","title":"SNAP 23 rabbit pAb","description":"\u003cp\u003eSNAP 23 rabbit pAb is an ELK Biotechnology antibody for research workflows involving SNAP 23.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eSpecificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin\/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin\/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle\/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins\/VAMPs. It is an essential component of the high affinity receptor for the\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eSNAP 23 Polyclonal Antibody detects endogenous levels of SNAP 23 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of HepG2 cells using SNAP 23 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 | Immunohistochemical analysis of paraffin-embedded human-ovary-cancer, antibody was diluted at 1:100 | Immunohistochemical analysis of paraffin-embedded human-ovary-cancer, antibody was diluted at 1:100 | Immunohistochemical analysis of paraffin-embedded mouse-brain, antibody was diluted at 1:100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186624835924,"sku":"ABM107774","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186624868692,"sku":"ABM97910","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES3961-c-1.jpg?v=1782046583","url":"https:\/\/www.abmium.com\/products\/elk-es3961-snap-23-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}