{"product_id":"elk-es3788-aplp-1-rabbit-pab","title":"APLP-1 rabbit pAb","description":"\u003cp\u003eAPLP-1 rabbit pAb is an ELK Biotechnology antibody for research workflows involving APLP-1.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eAPLP-1 Polyclonal Antibody detects endogenous levels of APLP-1 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of extracts from K562 cells, using APLP-1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 | Immunohistochemical analysis of paraffin-embedded mouse-ovary, antibody was diluted at 1:100 | Immunohistochemical analysis of paraffin-embedded mouse-ovary, antibody was diluted at 1:100 | Immunohistochemical analysis of paraffin-embedded mouse-ovary, antibody was diluted at 1:100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186612449620,"sku":"ABM107671","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186612482388,"sku":"ABM97807","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES3788-c-1.jpg?v=1782046192","url":"https:\/\/www.abmium.com\/products\/elk-es3788-aplp-1-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}