{"product_id":"elk-es3347-rgs1-rabbit-pab","title":"RGS1 rabbit pAb","description":"\u003cp\u003eRGS1 rabbit pAb is an ELK Biotechnology antibody for research workflows involving RGS1.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta\/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eRGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using RGS1 Polyclonal Antibody | Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using RGS1 Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from mouse muscle cells, using RGS1 Antibody. The lane on the right is blocked with the synthesized peptide. | Western blot analysis of the lysates from 293 cells using RGS1 antibody.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186550485332,"sku":"ABM107478","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186550518100,"sku":"ABM97614","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES3347-c-1.jpg?v=1782045713","url":"https:\/\/www.abmium.com\/products\/elk-es3347-rgs1-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}