{"product_id":"elk-es2521-histone-deacetylase-7a-rabbit-pab","title":"Histone deacetylase 7a rabbit pAb","description":"\u003cp\u003eHistone deacetylase 7a rabbit pAb is an ELK Biotechnology antibody for research workflows involving HDAC7.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation\/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eHistone deacetylase 7a Polyclonal Antibody detects endogenous levels of Histone deacetylase 7a protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using Histone deacetylase 7a Polyclonal Antibody | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HDAC7 Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of lysates from HUVEC cells, using HDAC7 Antibody. The lane on the right is blocked with the synthesized peptide. | Western blot analysis of the lysates from COLO205 cells using HDAC7 antibody.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186183156052,"sku":"ABM107136","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186183188820,"sku":"ABM97272","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES2521-c-1.jpg?v=1782043532","url":"https:\/\/www.abmium.com\/products\/elk-es2521-histone-deacetylase-7a-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}