{"product_id":"elk-es2425-gipr-rabbit-pab","title":"GIPR rabbit pAb","description":"\u003cp\u003eGIPR rabbit pAb is an ELK Biotechnology antibody for research workflows involving GIPR.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes. [provided by RefSeq, Oct 2011],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eGIPR Polyclonal Antibody detects endogenous levels of GIPR protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using GIPR Polyclonal Antibody | Immunofluorescence analysis of MCF7 cells, using GIPR Antibody. The picture on the right is blocked with the synthesized peptide. | Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using GIPR Antibody. The picture on the right is blocked with the synthesized peptide. | Western blot analysis of the lysates from HT-29 cells using GIPR antibody.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56186177814868,"sku":"ABM107089","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56186177847636,"sku":"ABM97225","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES2425-c-1.jpg?v=1782043580","url":"https:\/\/www.abmium.com\/products\/elk-es2425-gipr-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}