{"product_id":"elk-es1460-synaptotagmin-1-2-phospho-ser309-306-rabbit-pab","title":"Synaptotagmin 1\/2 (phospho Ser309\/306) rabbit pAb","description":"\u003cp\u003eSynaptotagmin 1\/2 (phospho Ser309\/306) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Synaptotagmin 1\/2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-Synaptotagmin 1\/2 (S309\/306) Polyclonal Antibody detects endogenous levels of Synaptotagmin 1\/2 protein only when phosphorylated at S309\/306.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using Phospho-Synaptotagmin 1\/2 (S309\/306) Polyclonal Antibody | Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide. | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Synaptotagmin (Phospho-Ser309) Antibody | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Synaptotagmin (Phospho-Ser309) Antibody. The picture on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56185478054228,"sku":"ABM105072","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56185478086996,"sku":"ABM95208","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES1460-c-1.jpg?v=1782035390","url":"https:\/\/www.abmium.com\/products\/elk-es1460-synaptotagmin-1-2-phospho-ser309-306-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}