{"product_id":"elk-es1451-ampkalpha1-2-phospho-thr183-172-rabbit-pab","title":"AMPKα1\/2 (phospho Thr183\/172) rabbit pAb","description":"\u003cp\u003eAMPKα1\/2 (phospho Thr183\/172) rabbit pAb is an ELK Biotechnology antibody for research workflows involving AMPKα1\/2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by this gene belongs to the ser\/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP\/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-AMPKα1\/2 (T183\/172) Polyclonal Antibody detects endogenous levels of AMPKα1\/2 protein only when phosphorylated at T183\/172.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56185473270100,"sku":"ABM105026","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56185473302868,"sku":"ABM95162","price":131.54,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/elk-es1451-ampkalpha1-2-phospho-thr183-172-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}