{"product_id":"elk-es1289-c-kit-phospho-tyr721-rabbit-pab","title":"c-Kit (phospho Tyr721) rabbit pAb","description":"\u003cp\u003ec-Kit (phospho Tyr721) rabbit pAb is an ELK Biotechnology antibody for research workflows involving c-Kit\/CD117.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThis gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003ePhospho-c-Kit (Y721) Polyclonal Antibody detects endogenous levels of c-Kit protein only when phosphorylated at Y721.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using Phospho-c-Kit (Y721) Polyclonal Antibody | Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using c-Kit (Phospho-Tyr721) Antibody | Western blot analysis of lysates from HepG2 cells treated with EGF 200ng\/ml 30', using c-Kit (Phospho-Tyr721) Antibody. The lane on the right is blocked with the phospho peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56185258443092,"sku":"ABM104246","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56185258475860,"sku":"ABM94382","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES1289-c-1.jpg?v=1782033346","url":"https:\/\/www.abmium.com\/products\/elk-es1289-c-kit-phospho-tyr721-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}