{"product_id":"elk-es11508-mrgrd-rabbit-pab","title":"MRGRD rabbit pAb","description":"\u003cp\u003eMRGRD rabbit pAb is an ELK Biotechnology antibody for research workflows involving MRGRD.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003efunction:May regulate nociceptor function and\/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,subcellular location:Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eMRGRD Polyclonal Antibody detects endogenous levels of protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56185027461460,"sku":"ABM103352","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56185027494228,"sku":"ABM93488","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES11508-c-1.jpg?v=1782029874","url":"https:\/\/www.abmium.com\/products\/elk-es11508-mrgrd-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}