{"product_id":"elk-es11506-lt4r1-rabbit-pab","title":"LT4R1 rabbit pAb","description":"\u003cp\u003eLT4R1 rabbit pAb is an ELK Biotechnology antibody for research workflows involving LT4R1.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003efunction:Receptor for extracellular ATP \u0026gt; UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.,PTM:Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.,\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eLT4R1 Polyclonal Antibody detects endogenous levels of protein.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56185027330388,"sku":"ABM103350","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56185027363156,"sku":"ABM93486","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES11506-c-1.jpg?v=1782029879","url":"https:\/\/www.abmium.com\/products\/elk-es11506-lt4r1-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}