{"product_id":"elk-es1107-ku-70-acetyl-lys539-rabbit-pab","title":"Ku-70 (Acetyl Lys539) rabbit pAb","description":"\u003cp\u003eKu-70 (Acetyl Lys539) rabbit pAb is an ELK Biotechnology antibody for research workflows involving Ku70\/XRCC6.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe p70\/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eAcetyl-Ku-70 (K539) Polyclonal Antibody detects endogenous levels of Ku-70 protein only when acetylated at K539.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184989188436,"sku":"ABM103070","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184989221204,"sku":"ABM93206","price":131.54,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/elk-es1107-ku-70-acetyl-lys539-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}