{"product_id":"elk-es1084-nfkappab-p65-mono-methyl-lys314-lys315-rabbit-pab","title":"NFκB-p65 (Mono Methyl Lys314\/Lys315) rabbit pAb","description":"\u003cp\u003eNFκB-p65 (Mono Methyl Lys314\/Lys315) rabbit pAb is an ELK Biotechnology antibody for research workflows involving NFkB p65.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eMono-Methyl-NFκB-p65 (K314\/K315) Polyclonal Antibody detects endogenous levels of p65 protein only when mono-methylated at K314\/K315.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of MCF7 cells using Mono-Methyl-NFκB-p65 (K314\/K315) Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184972411220,"sku":"ABM102937","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184972443988,"sku":"ABM93073","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES1084-c-1.jpg?v=1782029000","url":"https:\/\/www.abmium.com\/products\/elk-es1084-nfkappab-p65-mono-methyl-lys314-lys315-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}