{"product_id":"elk-es1040-cleaved-klk8-v33-rabbit-pab","title":"Cleaved-KLK8 (V33) rabbit pAb","description":"\u003cp\u003eCleaved-KLK8 (V33) rabbit pAb is an ELK Biotechnology antibody for research workflows involving KLK8.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCleaved-KLK8 (V33) Polyclonal Antibody detects endogenous levels of fragment of activated KLK8 protein resulting from cleavage adjacent to V33.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using Cleaved-KLK8 (V33) Polyclonal Antibody | Western blot analysis of lysates from Jurkat cells, treated with etoposide 25uM 24h, using Neuropsin (Cleaved-Val33) Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184924373332,"sku":"ABM102696","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184924406100,"sku":"ABM92832","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES1040-c-1.jpg?v=1782027820","url":"https:\/\/www.abmium.com\/products\/elk-es1040-cleaved-klk8-v33-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}