{"product_id":"elk-es1039-cleaved-klk11-i54-rabbit-pab","title":"Cleaved-KLK11 (I54) rabbit pAb","description":"\u003cp\u003eCleaved-KLK11 (I54) rabbit pAb is an ELK Biotechnology antibody for research workflows involving KLK11.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009],\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecificity\u003c\/th\u003e\n\u003ctd\u003eCleaved-KLK11 (I54) Polyclonal Antibody detects endogenous levels of fragment of activated KLK11 protein resulting from cleavage adjacent to I54.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern Blot analysis of various cells using Cleaved-KLK11 (I54) Polyclonal Antibody | Western blot analysis of lysates from HeLa cells, treated with etoposide 25uM 24H, using Kallikrein-11 (Cleaved-Ile54) Antibody. The lane on the right is blocked with the synthesized peptide.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184923849044,"sku":"ABM102690","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184923881812,"sku":"ABM92826","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ES1039-c-1.jpg?v=1782028023","url":"https:\/\/www.abmium.com\/products\/elk-es1039-cleaved-klk11-i54-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}