{"product_id":"elk-ept242-recombinant-human-il-13-c-fc","title":"Recombinant Human IL-13 (C-Fc)","description":"\u003cp\u003eRecombinant Human IL-13 (C-Fc) is an ELK Biotechnology recombinant protein for research use.\u003c\/p\u003e\u003ch3\u003eDescription\u003c\/h3\u003e\u003cp\u003eRecombinant Human Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Gly21 ­ Asn132 is expressed with a Fc tag at the C-terminus.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eInterleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.\u003c\/p\u003e\u003ch3\u003eHandling information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eReconstitution\u003c\/th\u003e\n\u003ctd\u003eAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg\/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDelivery condition\u003c\/th\u003e\n\u003ctd\u003eThe product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"10ug","offer_id":56187692056916,"sku":"ABM100966","price":221.31,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/elk-ept242-recombinant-human-il-13-c-fc","provider":"ABMIUM","version":"1.0","type":"link"}