{"product_id":"elk-ept121-recombinant-mouse-hgf-c-6his","title":"Recombinant Mouse HGF (C-6His)","description":"\u003cp\u003eRecombinant Mouse HGF (C-6His) is an ELK Biotechnology recombinant protein for research use.\u003c\/p\u003e\u003ch3\u003eDescription\u003c\/h3\u003e\u003cp\u003eRecombinant Mouse Hepatocyte Growth Factor is produced by our Mammalian expression system and the target gene encoding Gln33­Leu728 is expressed with a 6His tag at the C-terminus.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHGF, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R\/c-MET. HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis. It can also alter epithelium morphology by the induction of nectin‑1 alpha ectodomain shedding, an adhesion protein component of adherens junctions .\u003c\/p\u003e\u003ch3\u003eHandling information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eReconstitution\u003c\/th\u003e\n\u003ctd\u003eAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg\/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eDelivery condition\u003c\/th\u003e\n\u003ctd\u003eThe product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"10ug","offer_id":56187603845460,"sku":"ABM100845","price":176.87,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/elk-ept121-recombinant-mouse-hgf-c-6his","provider":"ABMIUM","version":"1.0","type":"link"}