{"product_id":"elk-ept002-recombinant-2019-ncov-nsp10-n-6his","title":"Recombinant 2019-nCoV NSP10 (N-6His)","description":"\u003cp\u003eRecombinant 2019-nCoV NSP10 (N-6His) is an ELK Biotechnology recombinant protein for research use.\u003c\/p\u003e\u003ch3\u003eDescription\u003c\/h3\u003e\u003cp\u003eRecombinant 2019-nCoV NSP10 is produced by our E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with a 6His tag at the N-terminus.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eNsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.\u003c\/p\u003e\u003ch3\u003eHandling information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eDelivery condition\u003c\/th\u003e\n\u003ctd\u003eThe product is shipped on dry ice\/polar packs. Upon receipt, store it immediately at the temperature listed below.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"50ug","offer_id":56187590476116,"sku":"ABM100726","price":745.67,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/products\/elk-ept002-recombinant-2019-ncov-nsp10-n-6his","provider":"ABMIUM","version":"1.0","type":"link"}