{"product_id":"elk-em1404-p63-alpha-3f11-mouse-mab","title":"P63-α (3F11) Mouse mAb","description":"\u003cp\u003eP63-α (3F11) Mouse mAb is an ELK Biotechnology antibody for research workflows involving P63-α (3F11).\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003ep63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of 1) A431 Cell Lysate, 2) 3T3 Cell Lysate , 3) PC-12 Cell Lysate using P63-α（EM1404）Mouse mAb diluted at 1:2000. | Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184894062932,"sku":"ABM102472","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184894095700,"sku":"ABM92608","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1404-c-1.jpg?v=1782027230","url":"https:\/\/www.abmium.com\/products\/elk-em1404-p63-alpha-3f11-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}