{"product_id":"elk-em1320-phospho-mlkl-s358-6b4-mouse-mab","title":"phospho-MLKL (S358) (6B4) Mouse mAb","description":"\u003cp\u003ephospho-MLKL (S358) (6B4) Mouse mAb is an ELK Biotechnology antibody for research workflows involving phospho-MLKL (S358) (6B4).\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-MLKL S358（EM1320）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Phospho-MLKL S358（EM1320）Mouse mAb diluted at 1:200.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184890491220,"sku":"ABM102442","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184890523988,"sku":"ABM92578","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1320-c-1.jpg?v=1782027135","url":"https:\/\/www.abmium.com\/products\/elk-em1320-phospho-mlkl-s358-6b4-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}