{"product_id":"elk-em1315-smad3-4c9-mouse-mab","title":"Smad3 (4C9) Mouse mAb","description":"\u003cp\u003eSmad3 (4C9) Mouse mAb is an ELK Biotechnology antibody for research workflows involving Smad3 (4C9).\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3\/SMAD4 complex, activates transcription.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of 1) Mouse Brain Tissue Lysate, 2) Rat Brain Tissue Lysate using Smad3（ EM1315）Mouse mAb diluted at 1:2000. | Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using Smad3（EM1315）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Smad3（EM1315）Mouse mAb diluted at 1:200.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184890261844,"sku":"ABM102439","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184890294612,"sku":"ABM92575","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1315-c-1.jpg?v=1782027118","url":"https:\/\/www.abmium.com\/products\/elk-em1315-smad3-4c9-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}