{"product_id":"elk-em1275-cystatin-c-7f11-mouse-mab","title":"Cystatin C (7F11) Mouse mAb","description":"\u003cp\u003eCystatin C (7F11) Mouse mAb is an ELK Biotechnology antibody for research workflows involving Cystatin C (7F11).\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunohistochemical analysis of paraffin-embedded Human Kidney Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184883380564,"sku":"ABM102423","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184883413332,"sku":"ABM92559","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1275-c-1.jpg?v=1782027084","url":"https:\/\/www.abmium.com\/products\/elk-em1275-cystatin-c-7f11-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}