{"product_id":"elk-em1261-a-actinin-4a12-mouse-mab","title":"a-actinin (4A12) Mouse mAb","description":"\u003cp\u003ea-actinin (4A12) Mouse mAb is an ELK Biotechnology antibody for research workflows involving a-actinin (4A12).\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eα-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunohistochemical analysis of paraffin-embedded Human Breast Carrcinoma Tissue using a-actinin（EM1261）Mouse mAb diluted at 1:200. | Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using a-actinin（EM1261）Mouse mAb diluted at 1:200.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184882889044,"sku":"ABM102416","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184882921812,"sku":"ABM92552","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1261-c-1.jpg?v=1782027063","url":"https:\/\/www.abmium.com\/products\/elk-em1261-a-actinin-4a12-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}