{"product_id":"elk-em1057-cdx2-mouse-mab","title":"CDX2 Mouse mAb","description":"\u003cp\u003eCDX2 Mouse mAb is an ELK Biotechnology antibody for research workflows involving CDX2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of 1) 293T, 2)Mouse Heart tissue with CDX2 mAb diluted at 1:2,000. | IHC staining of human rectal cancer tissue with CDX2 mouse mAb(14H6) diluted at 1:200.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184863523156,"sku":"ABM102279","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184863555924,"sku":"ABM92415","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1057-c-1.jpg?v=1782026758","url":"https:\/\/www.abmium.com\/products\/elk-em1057-cdx2-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}