{"product_id":"elk-ea347-atg4a-rabbit-pab","title":"ATG4a Rabbit pAb","description":"\u003cp\u003eATG4a Rabbit pAb is an ELK Biotechnology antibody for research workflows involving ATG4a.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eAutophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A\/autophagin-2, Atg4B\/autophagin-1, Atg4C\/autophagin-3, and Atg4D\/autophagin-4).\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using ATG4a （EA347）Rabbit pAb diluted at 1:200 | Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using ATG4a （EA347）Rabbit pAb diluted at 1:200\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184852480340,"sku":"ABM102211","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184852513108,"sku":"ABM92347","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EA347-c-1.jpg?v=1782026603","url":"https:\/\/www.abmium.com\/products\/elk-ea347-atg4a-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}