{"product_id":"elk-ea230-alpha-actinin-rabbit-pab","title":"α-actinin Rabbit pAb","description":"\u003cp\u003eα-actinin Rabbit pAb is an ELK Biotechnology antibody for research workflows involving α-actinin.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eα-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of 1) 3T3, 2)PC12, 3)Rat Heart Tissue with α-actinin Rabbit pAb EA230 diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded Mouse KidneyTissue using α-actinin （EA230）Rabbit pAb diluted at 1:500.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184841699668,"sku":"ABM102105","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184841732436,"sku":"ABM92241","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EA230-c-1.jpg?v=1782026353","url":"https:\/\/www.abmium.com\/products\/elk-ea230-alpha-actinin-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}