{"product_id":"elk-ea147-beta-catenin-rabbit-pab","title":"β-Catenin Rabbit pAb","description":"\u003cp\u003eβ-Catenin Rabbit pAb is an ELK Biotechnology antibody for research workflows involving β-Catenin.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of 1) 3T3, 2)Rat Liver, with β-Catenin Rabbit pAb EA147 diluted at 1:2,000. | Immunohistochemical analysis of paraffin-embedded human breast caricnoma using β-catenin（EA147）Rabbit pAb diluted at 1:500.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184835866964,"sku":"ABM102039","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184835899732,"sku":"ABM92175","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EA147-c-1.jpg?v=1782026195","url":"https:\/\/www.abmium.com\/products\/elk-ea147-beta-catenin-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}