{"product_id":"elk-ea024-cox2-cyclooxygenase-2-rabbit-pab","title":"COX2\/Cyclooxygenase 2 Rabbit pAb","description":"\u003cp\u003eCOX2\/Cyclooxygenase 2 Rabbit pAb is an ELK Biotechnology antibody for research workflows involving COX2\/Cyclooxygenase 2.\u003c\/p\u003e\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eProstaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eWestern blot analysis of Hela with COX2 Rabbit Polyclonal antibody diluted at 1:1,000.\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184832852308,"sku":"ABM101997","price":220.41,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184832885076,"sku":"ABM92133","price":131.54,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EA024-c-1.jpg?v=1782026117","url":"https:\/\/www.abmium.com\/products\/elk-ea024-cox2-cyclooxygenase-2-rabbit-pab","provider":"ABMIUM","version":"1.0","type":"link"}