{"product_id":"citrate-buffer-powder-ar0024","title":"Citrate Buffer Powder","description":"Boster’s Citrate Buffer Pack is an IHC antigen retrieval reagent used in heat induced epitope retrieval (HIER) for recovery of antigens masked by cross-linking during fixation.\u003cp\u003eIn immunohistochemistry (IHC) the most commonly used fixatives for preserving cell morphology and tissue architecture cause cross-linkages that mask epitopes, leading to poor or no staining. To reverse the loss of antigenicity and enable the primary antibodies to bind antigens, Heat-Induced Epitope Retrieval (HIER) is used to unmask epitopes by breaking the methylene bridges formed during fixation. During the process of HIER the buffer helps unfold the proteins, improving the accessibility of antibodies to tissue antigens. Citrate buffer solution is the preferred antigen retrieval buffer for most antibodies during HIER.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003eSupplier\u003c\/th\u003e\n\u003ctd\u003eBoster Bio\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eABMIUM evidence status\u003c\/th\u003e\n\u003ctd\u003eABMIUM Verified™ collaborator-tested data\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eCatalogue reference\u003c\/th\u003e\n\u003ctd\u003eAR0024\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eProduct category\u003c\/th\u003e\n\u003ctd\u003eAssistive reagents\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eReactive species\u003c\/th\u003e\n\u003ctd\u003eNot specified\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eTested applications\u003c\/th\u003e\n\u003ctd\u003eIHC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003eStore at room temperature (RT) for one year\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth\u003eNCBI Gene ID\u003c\/th\u003e\n\u003ctd\u003e294526\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\u003c\/table\u003e\u003ch3\u003eAvailable variants\u003c\/h3\u003e\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eConjugation\u003c\/th\u003e\n\u003cth\u003eSize\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eNot applicable\u003c\/td\u003e\n\u003ctd\u003e1 pack\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Boster Bio","offers":[{"title":"1 pack","offer_id":56042413883732,"sku":"ABM31280","price":3.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/citrate_buffer_solution.png?v=1780833562","url":"https:\/\/www.abmium.com\/products\/citrate-buffer-powder-ar0024","provider":"ABMIUM","version":"1.0","type":"link"}